The National Action Plan for Combating Antibiotic-Resistant Bacteria 2020-2025 is a national cross-sectoral action plan of the United States of America. This Plan continues to prioritise infection prevention and control to slow the spread of resistant infections and reduce the need for antibiotic use. To ensure that patients receive the right antibiotic care, the Plan supports innovative approaches to developing and deploying diagnostic tests and treatment strategies. A One Health approach, which recognises the relationships between the health of humans, animals, plants, and the environment, is integrated throughout the Plan, with an expanded effort to understand antibiotic resistance in the environment. The Plan also focuses on collecting and using data to better understand where resistance is occurring, support the development of new diagnostics and treatment options, and advance international coordination. The Plan further provides to slow the emergence of resistant bacteria and prevent the spread of resistant infections; expand national, regional, and State capacity for detecting, containing, and preventing antibiotic-resistant infections; engage the public and other stakeholders to develop, expand, and increase national and State education, training, and communication campaigns focused on using antibiotics responsibly, stopping the spread of antibiotic resistance, and preventing infections and life-threatening conditions like sepsis; develop and implement policies and practices to promote the responsible use of antibiotics; develop and implement evidence-based policies and practices to prevent infections and stop the spread of antibiotic resistance across One Health; strengthen national one health surveillance efforts to combat resistance; strengthen testing and training capacities and capabilities, enhance integration and harmonisation of testing data, and expand the reach of Federal antibiotic resistance laboratory networks across One Health; continue expanding and improving access to specimen and data repositories for research and innovation; strengthen the national infrastructure for antibiotic resistance surveillance data across One Health, by improving capacity, utility, timeliness, and the use of harmonised terminology; strengthen the national infrastructure for antibiotic use surveillance data across One Health, by improving capacity, utility, timeliness, and the use of harmonised terminology; advance development and use of rapid and innovative diagnostic tests for identification and characterisation of resistant bacteria; develop and validate new diagnostics; support research to determine the appropriate use of diagnostics; stimulate the appropriate adoption and use of diagnostics; accelerate basic and applied research and development for new antibiotics, other therapeutics, and vaccines; expand basic and applied interdisciplinary research to better understand the emergence, spread, and persistence of antibiotic resistance, and develop mitigation strategies for antibiotic resistance in human, animal, agricultural, and environmental settings; intensify basic, translational, and clinical research to support the discovery and development of new treatments, including antibiotics, non-traditional therapeutics, and optimised treatment regimens; intensify basic, translational, and clinical research to support the discovery and development of new preventative products or strategies; enhance efforts to promote sustainability of the commercial market for new antibiotic products; improve international collaboration and capacities for antibiotic-resistance prevention, surveillance, control, and antibiotic research and prevention; enhance U.S. leadership in the global fight against antibiotic resistance; promote increased awareness and capacity in countries to address the emergence and slow the spread of antibiotic resistance; generate consistent and actionable global data on antibiotic resistance, including by extending CDC’s (Centres for Disease Control and Prevention) Antibiotic Resistance Lab Network to global sites to address the identification, emergence, spread, and effects of antibiotic resistance; and increase international collaborations to facilitate basic, translational, and clinical research into understanding the causes of antibiotic resistance and developing countermeasures. The U.S. Government will report annually on progress toward the objectives set in the Plan.
United States of America · 2020-10-01